Phylogenetic Shifts in Gene Body Methylation Correlate with Gene Expression and Reflect Trait Conservation
نویسندگان
چکیده
منابع مشابه
Gene Expression and Methylation Pattern in HRK Apoptotic Gene in Myelodysplastic Syndrome
Myelodysplastic syndromes (MDSs) are a clonal bone marrow (BM) disease characterized by ineffective hematopoiesis, dysplastic maturation and progression to acute myeloid leukemia (AML). Methylation silencing of HRK has been found in several human malignancies. In this study, we explored the association of HRK methylation status with its expression, clinical parameters and MDS subtypes in MDS pa...
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myelodysplastic syndromes (mdss) are a clonal bone marrow (bm) disease characterized by ineffective hematopoiesis, dysplastic maturation and progression to acute myeloid leukemia (aml). methylation silencing of hrk has been found in several human malignancies. in this study, we explored the association of hrk methylation status with its expression, clinical parameters and mds subtypes in mds pa...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2019
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msz195